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KMID : 0613820070170121695
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Journal of Life Science
2007 Volume.17 No. 12 p.1695 ~ p.1700
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Growth Inhibition of Helicobacter pylori by Ingestion of Fermented Soybean Paste
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Kim Hyung-Rak
Kim Young-Hyu
Park Seong-Chan
Kim Mi-Sun
Baik Keun-Sik
Cho Hyun-Wook
Seong Chi-Nam
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Abstract
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The aim of this study was to estimate the ingestion effect of fermented soybean paste on the growth inhibition of Helicobacter pylori. Anti-H. pylori effect of the aqueous extract of soybean paste and cell-free supernatant of the isolates from soybean paste were determined using agar diffusion method. Soybean paste and the isolates inhibited the growth of H. pylori. Effect of soybean paste ingestion was estimated using urea breath test against infected volunteers showing no symptom of gastric disease. When 10 g of soybean paste was ingested 3 times a day for 6 weeks, average value of P= Δ13C (T1- T0) decreased from P=58 to P=28. This result indicated that fermented soybean paste was effective to inhibit the growth of H. pylori in gastric tissue.
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KEYWORD
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Fermented soybean paste, Helicobacter pylori, ingestion, urea breath test
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